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ctt-journal > Pavlova G. et al. (Abstract)

Pavlova G. et al. (Abstract)

Cellular Therapy and Transplantation (CTT), Vol. 3, No. 12
doi: 10.3205/ctt-2011-No12-abstract65

© The Authors. This abstract is provided under the following license: Creative Commons Attribution 3.0 Unported

Abstract accepted for "5th Raisa Gorbacheva Memorial Meeting Hematopoietic Stem Cell Transplantation in Children and Adults", Saint Petersburg, Russia, September 18–20, 2011

Preliminary Program

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Pediatric cancer epidemiology in Chuvashia (1994–2007)

Galina P. Pavlova, Albina M. Sergeeva

Chuvashia Ministry of Public Health and Social Development, Republican Pediatric Hospital, Cheboksary, Russia

Correspondence: Albina M. Sergeeva, Chuvashia Ministry of Public Health and Social Development Republican Pediatric Hospital, 6/8, Gladkova str., Cheboksary, 428020, Russia, E-mail: bmt@spam is badspmu.rssi.ru

Abstract

Aim: This study was aimed at defining the epidemiology of leukemia and solid tumors and thereby the demand for hematopoietic stem cell transplantation (HSCT) in the Chuvashia pediatric population (1–15 years) for the period of 1997–2007.

Methods: Data on pediatric morbidity for the period of 1997–2007 was obtained from the Chuvashia Federal Statistical Bureau (Chuvashstat), regional Federal Oncology Registry, and reports from local pediatric and hematology departments. Demographics data was obtained from the Chuvashia Federal Medical Analytical Center database.

Results: For the period of 1997–2007 a total of 402 pediatric patients with cancer were registered. Most of the patients were diagnosed with acute leukemia (34.6%), CNS tumors (14.42%), and lymphomas (10.69%); with less common positions held by solid tumors, histiocytoses, and chronic myeloid leukemia. There was a tendency toward an increase in pediatric cancer incidence from 4.3 (1994–200) to 6.26 per 100,000 of the pediatric population (2000–2007). While leukemia incidence was relatively stable (5.78 and 5.18), there was an increase in the proportion of solid tumors from 4.3 to 6.26. There was a slight male prevalence with male/female ratio of 1.12:1.0. There were 2 peaks of disease incidence in the age of 0–5 years (mostly leukemia and neuroblastomas) and 11–15 years (leukemia, CNS tumors, and bone tumors). The preliminary analysis of the patient population revealed 1.2–1.6 potential HSCT recipients per 100,000 of the pediatric population per year (3–4 patients a year for overall pediatric population).

Conclusions: The most common pediatric cancers in Chuvashia are leukemia, CNS tumors, and lymphomas. There is a trend to increased pediatric cancer incidence due to an increase in the number of solid tumors. The overall demand in the 1994–2007 period for HSCT was 3–4 patients a year.

Keywords: epidemiology, Chuvashia, cancer incidence, hematopoietic stem cell transplantation demand